The game I'm really looking forward too, has to be Starcraft 2. I've been looking forward to this game since I first played Starcraft 1, What a Game!! The sequal should be amazing. Blizzard really need to get of their behinds, We've been waiting almost ten years!! I have a feeling that they have actually been working on it for about a year or so allready, but untill they release the expansion for their cashcow World of Warcraft, I doubt that they will annouce it. Blizzard have a habit of being very secretive about their releases.
I'm also really looking forward to the Red Alert 3. EA ( they took over westwood, the creaters of the C & C brand ) sent out emails to people of their mailing list informing them, that they are hiring all the main people that worked on the old games to work on Red Alert 3. Good move if you ask me, have you ever played C & C Generals or renegade? tut..tut. tut..
The expansion for Civilization 4 should be really cool too. The expansions for the 3 were really cool, added quite alot of new content.